Cannabinoid receptor expression at the MNTB-LSO synapse in developing rats
نویسندگان
چکیده
منابع مشابه
Regulating Receptor Levels at a Developing Synapse
differentiation in target cells at neuron–neuron syn-and indicates that neither activity nor the previous exis-apses. However, the postsynaptic markers used in this tence of NMDA receptors at a synapse is necessary study, although good indicators of postsynaptic differ-for insertion of GluR1-containing AMPA receptors into entiation, may not be the earliest postsynaptic mole-synapses. cules to c...
متن کاملPre- and postsynaptic properties of glutamatergic transmission in the immature inhibitory MNTB-LSO pathway.
The lateral superior olive (LSO) integrates excitatory inputs driven by sound arriving at the ipsilateral ear with inhibitory inputs driven by sound arriving at the contralateral ear in order to compute interaural intensity differences needed for localizing high-frequency sound sources. Specific mechanisms necessary for developmental refinement of the inhibitory projection, which arises from th...
متن کاملMaturation of Calcium-Dependent GABA, Glycine, and Glutamate Release in the Glycinergic MNTB-LSO Pathway
The medial nucleus of the trapezoid body (MNTB) is a key nucleus in high-fidelity temporal processing that underlies sound localization in the auditory brainstem. While the glycinergic principal cells of the MNTB project to all primary nuclei of the superior olive, during development the projection from MNTB to the lateral superior olive (LSO) is of interest because this immature inhibitory pro...
متن کاملTitle : Pre - and post - synaptic properties of glutamatergic transmission in the immature inhibitory
The lateral superior olive (LSO) integrates excitatory inputs driven by sound arriving at the ipsilateral ear with inhibitory inputs driven by sound arriving at the contralateral ear in order to compute interaural intensity differences needed for localizing high frequency sound sources. Specific mechanisms necessary for developmental refinement of the inhibitory projection, which arises from th...
متن کاملPreferential epithelial expression of type-1 cannabinoid receptor (CB1R) in the developing canine embryo.
The use of cannabinoid receptor agonists is gaining a strong interest both in human and veterinary medicine. The potential use of cannabimimetic compounds in companion animals was reviewed in 2007 for their role in tissue inflammation and pain. A better knowledge of type-1 cannabinoid receptor (CB1R) expression on the target population may help in risk management in order to prevent unwanted si...
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ژورنال
عنوان ژورنال: Neuroscience Letters
سال: 2012
ISSN: 0304-3940
DOI: 10.1016/j.neulet.2011.12.047